Spectrophotometric analysis of cytochromes in Morris hepatomas.
نویسندگان
چکیده
levels of cytochrome c in mitochondria, giving a low a + as/c ratio, and (b) low contents of cytochromes ¿>5 and P-450 in microsomes. Analysis in whole homogenates of hepatomas showed more pronounced decrease of the amount of cytochrome a + a3, presumably due to the decrease of the number of mitochondria in hepatoma cells. The livers of the tumor-bearing rats are also characterized by the similar, although less significant, cytochrome pattern observed in tumors. A low a + a3/c ratio was also observed in embryonic livers, whereas regenerating liver showed no significant difference in the content of cytochromes as compared to that of the normal adult liver.
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عنوان ژورنال:
- Cancer research
دوره 33 11 شماره
صفحات -
تاریخ انتشار 1973